Influence of Sublethal Lead Concentrations on Glucose, Serum Enzymes and Ion Levels in Tilapia (Oreochromis mossambicus)

In this study, alterations in glucose, blood enzymes (alkaline phosphatase (ALP), lactate dehydrogenase (LDH), alanine transaminase (ALT), aspartate aminotransferase (AST)) and serum ion (P, Mg, Cl, Ca, Fe) levels were investigated in Tilapia (Oreochromis mossambicus), which were semi-statically exposed to different lead concentrations in vivo. The fish were exposed to low (0.5 mg/L), medium (2.5 mg/L) and high (5 mg/L) concentrations of lead during 14 days. At the end of the experiment, biochemical blood parameters such as glucose, ALP, LDH, AST, chloride and magnesium increased (p<0.05). While, LDL and calcium levels decreased (p<0.05); ALT, cholesterol, albumin, iron and phosphor were fluctuated (p<0.05). Consequently, it was found that exposure of O. mossambicus to lead concentrations affected serum biochemical parameters negatively.